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Cell Signaling Technology Research Associate I - IHC in Danvers, Massachusetts

Cell Signaling Technology, Inc. (CST) is a worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed PTMScan®, a technology to discover protein post-translational modifications, PhosphoSitePlus®, an online resource for investigation of post-translational modifications, and XMT® technology, a proprietary method to develop exceptional monoclonal antibodies. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

We are seeking a highly self-motivated Research Associate to be part of our Immunohistochemistry Group. The mission of the Immunohistochemistry Group is to serve as a core provider of immunohistochemical analysis of cells and tissues in support of the Product Development and Production. Team members are responsible for delivery of thorough, high quality paraffin-embedded cell pellets and tissues within established service level agreements and continued monitoring of processes in order to reduce testing times.

  • Culture and treat mammalian cell lines

  • Perform sterile technique in Tissue Culture, including culturing and passaging cell lines

  • Routine cleaning and stocking of the Tissue Culture room and biosafety cabinet

  • Preparing high quality paraffin-embedded cell pellets to facilitate IHC testing

  • Conducting scientific experiments including western blots to verify treatment efficacy

  • Preparing paraffin-embedded animal tissues, syngeneic tumors and xenografts in conjunction with the Animal Facility staff

  • Maintaining the inventory of paraffin-embedded human tissues, including sample logging and management of associated clinical data, when applicable

  • Meeting established service level agreements for delivery of all paraffin-embedded materials

  • Maintaining tissue processing and embedding equipment per established policies

  • Supporting the execution of IHC testing as appropriate opportunities arise

  • Maintaining accurate and complete laboratory documentation in appropriate systems and testing databases in accordance with CST quality systems requirements

  • Developing an understanding of the antibody development process and maintaining an awareness of such as changes are implemented

  • Understanding and following established protocols for all established group processes and procedures as detailed in SOPs and training documents

  • Seeking opportunities that will improve quality, efficiency, or scalability of cell culture and other team processes

  • Adhering to safety procedures in and around the laboratory

  • Bachelor’s degree in a biological science

Preferred Skills/Experience

  • Previous experience with tissue culture

  • Multi-tasking with effective management of multiple, changing priorities

  • Strong organizational skills

  • Attention to detail

  • Strong verbal and written communication skills

  • Highly dependable and team-focused

Cell Signaling Technology, Inc. is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

ID: 2021-1419

External Company URL:

Street: 3 Trask Lane

Telecommute: No