Massachusetts Institute of Technology Technical Associate, Shalek Lab in Cambridge, Massachusetts
Technical Associate, Shalek Lab
Job Number: 21537
Functional Area: Research - Engineering
Department: Institute for Medical Eng. and Science
School Area: Engineering
Employment Type: Full-Time
Employment Category: Exempt
Visa Sponsorship Available: No
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Information on MIT’s COVID-19 vaccination requirement can be found at the bottom of this posting.
TECHNICAL ASSOCIATE, SHALEK LAB (https://imes.mit.edu/people/faculty/shalek-alex-k/) , Institute for Medical Engineering and Science (IMES), to join a lab specializing in leveraging novel single-cell genomic approaches to understand the behaviors of complex biological systems. Will focus on human cancers, both liquid (e.g., leukemias and lymphomas) and solid (e.g., pancreatic ductal adenocarcinoma) tumors. Research questions center on the ecosystem of various tumors and how their malignant transcriptional phenotypes relate to the local microenvironment. The core technique used is Seq-Well, a customizable, in-house platform for single-cell RNA-sequencing (scRNA-seq) and library generation from thousands of cells. Responsibilities include conducting standard and specialized laboratory techniques; collecting and analyzing data from experiments and improving protocols; recording, summarizing, and documenting findings; maintaining inventories of laboratory supplies; managing/maintaining databases; serving as the laboratory safety officer; preparing lab for inspections; participating in onboarding new lab staff; assessing equipment needs and schedule maintenance/repairs; and performing other duties as assigned. May perform other RNA-seq biological assays with Seq-Well and SmartSeq 2 and co-author articles/manuscripts. Full description available at https://imes.mit.edu/about/career-opportunities/.
REQUIRED: bachelor’s degree in a biology-, chemistry-, or immunology-related field; two years’ wet lab bench experience and/or experimental laboratory experience; experience with sterile technique and cell culture; desire to understand tumor biology and therapy resistance through a single-cell lens; excellent organizational, analytical, and communication skills; attention to detail; and self-direction and self-motivation. Must be able to work on and juggle multiple concurrent projects/responsibilities while meeting deadlines and tracking deliverables; and work with minimal supervision and as a productive team member in a rapidly evolving work environment. PREFERRED: virus work experience, background in virology, knowledge of R and/or other programming languages, and coursework experience related to cancer. Job #21537 7/8/22