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Harvard University Research Assistant III Lab in Cambridge, Massachusetts

52693BRAuto req ID:52693BRJob Code:403116 Research Assistant III Lab Location:USA - MA - Boston Business Title:Research Assistant III - Human Cerebral OrganoidsSub-Unit:Wyss Institute Salary Grade:054Time Status:Full-time Union:55 - Hvd Union Cler & Tech Workers Basic Qualifications:

  • Bachelor’s degree in biology, biological/biomedical engineering, pharmacology or related field.

  • Minimum of 2 years’ experience in a lab environment. Education may count towards years of experience.

Additional Qualifications and Skills:

  • Tissue culture experience, particularly with human primary cells, is required.

  • Tissue modeling of human disease is a plus.

  • Experience performing immunohistochemistry, fluorescence microscopy and ImageJ, is a plus.

  • Experience performing RT-qPCR and RNAseq, is a plus.

  • Experience with animal models.

Additional Information:

Offer contingent on successful completion of pre-placement medical evaluation. This is a one year term position with the possibility of renewal.

The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.

Harvard offers an outstanding benefits package including:

  • Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 11.5 paid holidays, and 3 paid personal days per year.

  • Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.

  • Retirement: University-funded retirement plan contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.

  • Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.

  • Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.

  • Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation and complimentary health services.

  • Harvard access to athletic facilities, libraries, campus events and many discounts throughout metro Boston.

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Department:Wyss InstitutePre-Employment Screening:Education, IdentitySchedule:

Monday through Friday, 9am - 5pm

Job Function:Research Job-Specific Responsibilities:

The candidate will work within a highly collaborative team of academic and industrial engineers, biologists, and bioinformaticians focused on therapeutics discovery and development, supporting the discovery of therapeutics for neurological disorders, in particular bipolar disorder. The candidate will be responsible for organoid culture and maintenance, molecular assays, and transcriptome sequencing, microscopy imaging. The position will apply several novel systems, CRISPR-generated Xenopus tadpole models of disease, behavior and cognitive screening platforms, and human iPSC-derived cerebral organoids, to screen drugs predicted using machine learning for efficacy in bipolar disorder models.

The successful candidate will play a key role in the design, execution, and analysis of experiments as well as interfacing with bioinformatics and engineering teams in a fast-paced team-focused environment. The candidate will report to the senior staff scientist and is expected to contribute to internal reports, patent applications, presentations, and publications. He/she will also assist with maintenance and procurement of equipment and supplies relating to tissue culture, microscopy, sequencing, and experimentation. This position offers an exciting opportunity to learn a broad spectrum of skills while pursuing challenging biological questions with clear commercialization potential.School/Unit:Harvard Medical School EEO Statement:We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.Job Summary:The Wyss Institute for Biologically Inspired Engineering at Harvard University seeks a talented, creative, and enthusiastic individual to join our community as a Research Assistant III to contribute to the discovery of novel classes of therapeutics using human cerebral organoids.

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