Dana-Farber Cancer Institute Research Technician - Center for Immuno-Oncology (Immune Assessment Lab) in Boston, Massachusetts

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Center for Immuno-Oncology established the Immune Assessment Laboratory to assist investigators at Dana-Farber Cancer Institute, its partners and external sites in establishing mechanistic and biomarker endpoints for clinical studies. With the recent success of immunotherapies through vaccines and checkpoint blockade targeted monoclonal antibodies, the goal of our Laboratory is to provide researchers with access to the latest innovations in immune monitoring in a quality-controlled setting.

The Lab offers technical support and scientific advice to investigators at Dana-Farber Cancer Institute and its partners who are interested in performing clinical studies related to cancer immunotherapies.

We provide data generation for clinical trials across multiple disease centers as well as the necessary expertise to design and develop assays related to cancer immunology biomarkers.

We are also involved in the collection of blood and solid tissue from patients participating in more than 30 clinical trials at DFCI as well as multiple external sites.

Our Lab is equipped with the latest technologies for the detection of soluble biomarkers, next generation sequencing, as well as determining cellular phenotypes.

  • Prepares and maintains tissue cultures

  • Operates instruments and equipment such as spectrophotometer, centrifuges, fluorimeter, incubators and light microscopes

  • Perform protein detection techniques such as ELISAs and flow cytometry

  • Manages and maintains database containing experimental results and reagent information and storage locations

  • Conducts literature reviews to assist in determining most suitable methods to be used in research

  • Prepares and presents written or oral progress reports concerning studies, including assembly, organization and interpretation of data

  • Performs statistical analysis of data

  • Prepares laboratory reagents, chemicals, instruments and equipment

  • Orders chemicals, reagents and other laboratory supplies

  • Performs routine maintenance and minor repairs of laboratory apparatus and instruments

  • Maintains a clean, orderly work area within the laboratory

  • Undertakes standard decontamination procedures prior to disposal of certain laboratory materials

  • Functions as the laboratory safety officer, responsible for compliance with all regulatory requirements, and the safe use of hazardous materials in the laboratory, including radioactive, biological and chemical agents

  • May demonstrate and explain various laboratory techniques to laboratory personnel, students and others

  • Maintains established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control

  • Performs all other duties and responsibilities as directed

  • BA/BS degree in Biology or healthcare related science

  • Preparation of media, tissue culture and assays reagents

  • Blood handling, and immune cells isolation and purification related techniques is a plus

  • Experience in cell culture techniques including culture, maintenance and storage of mammalian cell lines is highly preferred.

  • ELISAs and flow cytometry experience (preferred)

  • Keep regular, detailed and accurate documentation of lab activities

  • Knowledge of Microsoft Word, Excel and other Windows-based software

  • Demonstrates exceptional organizational, communication and interpersonal skills

  • The successful candidate will be a team-oriented, bench scientist. He or she must be self-motivated, and detail-oriented. The candidate should be an effective communicator

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

Job ID: 2018-10187

Grade: 17

External Company URL: www.dana-farber.org